Blastocystis Antigens Induce IL-1B, IL-6, and TNF-alpha Expression in Murine Intestinal Explants

Researchers from the National University of Singapore have published a study in the journal Infection and Immunity reporting that Blastocystis antigens produce statistically significant increases in expression of proinflammatory cytokines such as IL-1Beta, IL-6, and TNF-alpha in mouse intestinal explants.   Serine proteases produced by Blastocystis were found to play a significant role in ERK and cytokine expression in the murine cells.  The text of the study is available from Infection and Immunity.


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