Multiplex DNA panel identifies many gastrointestinal pathogen not found in microscopy from pediatric patients returning from the tropics

Researchers in Switzerland studying 312 stool samples from pediatric patients returning from trips to the tropics report that conventional laboratory methods failed to identify most of the norovirus-positive and Giardia-positive samples identified by Luminex’s xTag gastrointestinal pathogen panel.  The Luminex panel covers 15 diarrhea-causing organisms using PCR amplification.  All adenovirus, rotavirus, C. diff, and Cryptosporidium samples were confirmed in external labs, but norovirus and Giarida positive samples were only idneitifes 40% and 29% of the time respectively.  For more information, refer to the paper published in the journal Infection.

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